Orientation-specific responses to sustained uniaxial stretching in focal adhesion growth and turnover
نویسندگان
چکیده
منابع مشابه
Orientation-specific responses to sustained uniaxial stretching in focal adhesion growth and turnover.
Cells are mechanosensitive to extracellular matrix (ECM) deformation, which can be caused by muscle contraction or changes in hydrostatic pressure. Focal adhesions (FAs) mediate the linkage between the cell and the ECM and initiate mechanically stimulated signaling events. We developed a stretching apparatus in which cells grown on fibronectin-coated elastic substrates can be stretched and imag...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2013
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1221637110